Jun
30
Drinking several cups of coffee a day could halt the development of multiple sclerosis, the results of a new study suggest.
Researchers hope that the finding may prove to be relevant for other autoimmune diseases, in which the body uses the weapons of its immune system against itself, such as rheumatoid arthritis and lupus.
“This is an exciting and unexpected finding, and I think it could be important for the study of MS and other diseases,” said Prof Linda Thompson of Oklahoma Medical Research Foundation, who reports the find in the Proceedings of the National Academy of Sciences.
In the study, done in collaboration with Dr Jeffrey Mills and Dr Margaret Bynoe of Cornell University, Ithaca, New York, along with colleagues in Finland’s University of Turku, researchers followed the progress of mice that normally developed an MS-like condition as a result of being injected with a vaccine that provoked an immune attack that damages nerves..
The scientists discovered that when the rodents consumed the equivalent of six to eight cups of coffee a day, they did not develop the condition. The finding could lead to new ways to prevent and treat MS, said Prof Thompson.
According to Prof Thompson, the caffeine acted on adenosine (one of the four building blocks in DNA) and this prevented certain T cells - white blood cells that play a central role in immune responses - from reaching the central nervous system and triggering the cascade of events that lead to experimental autoimmune encephalomyelitis, or EAE, the animal model for the human disease MS.
read the rest: Coffee could halt multiple sclerosis - Telegraph
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