Apr
10
Pregnant multiple sclerosis patients have long noticed a sharp reduction in their symptoms - only to see them reappear after giving birth.
It’s what tipped off researchers to the potential power of estriol, a type of estrogen that surges during the second and third trimesters of pregnancy to help prevent the body from rejecting the fetus. But new research shows it may do much more.
In a pilot study at UCLA, women took Trimesta, a synthesized form of estriol used in Europe and Asia for treating hot flashes. They showed an 80 percent reduction in M.S.-related lesions on the brain within three months of treatment. After six months, their cognitive function improved by 14 percent.
Now the Pipex Pharmaceuticals drug is being studied at the University of Utah and six other sites in the country in a three-year, Phase II clinical study.
Study uses hormones to treat multiple sclerosis - Salt Lake Tribune
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